Moreover, low and high elastance phenotypes can be distinguished in mechanically ventilated patients, based on lung mechanics, ventilation-to-perfusion ratio, and CT scans these two phenotypes have presumed differences in their underlying pathophysiology.
Clinically, three stages have been identified based on viral infection, pulmonary involvement with inflammation, and fibrosis. Since the outbreak of the COVID-19 pandemic, much has been learned regarding its clinical course, prognostic inflammatory markers, disease complications, and mechanical ventilation strategy.
